Primary Complex (PTB) Treatment

For the couples of months, my daughter experience recurrent colds and cough.  If there is a fever, we brought him to the physician and he advised to take antibiotic.  After taking the complete course of antibiotic, my daughter will heal for sometime but after a month there is another cold and cough that is on and off. So, we decided to take her to the pediatrician to closely monitor her health.

Her pediatrician advised her to take loradine phenylephrine, meptin, pred10 and co-amoxiclav.  After taking these medicines, the symptoms are temporary disappear so her pediatrician decided to have chest xray examination to further evaluation of the symptoms.

When I and my husband see the x-ray result, it impression result is “bilateral primary (PTB), we feel sad because we knew that medicine for primary complex should be taken for 6 months or more.  A lot of sacrifice and perseverance is necessary in order to a child to fully cure because a tuberculosis bacterium which is the mycobacterium tuberculosis is hard to kill. Also, the pedia advised us to both of us should have x-ray to determine if we were infected.

Primary complex is not contagious but tuberculosis in adult is very contagious so it is important to stay away from adult who have positive xray result for TB.  But of course, if adult is taking TB medicine for about 2 to 3 weeks, tuberculosis is no longer contagious.

Tuberculosis Signs and Symptoms

My daughter was diagnosed with Primary Complex that’s why her pediatrician was required me and my husband to have chest x-ray to be able to know the source of infection.  So I asked our general physician regarding the signs and symptoms of tuberculosis since primary complex is also cause by tuberculosis bacteria known as mycobacterium tuberculosis.

The typical signs and symptoms of TB, tuberculosis are persistent or chronic cough with sputum production and with blood if in the advanced stage, fatigue, lack of appetite, unexplainable weight loss, fever and night sweats.  The mode of transmission of tuberculosis is mainly by droplet infection and droplet nuclei produced when an adult or patient who has tuberculosis coughs. When coughing, speaking or sneezing, droplets are expelled into the air. Droplets dry out quickly but the bacteria can remain airborne for hours.

Chest xray and PPD skin test are used to diagnose tuberculosis.  Also, it can diagnose sputum microscopic examination.  Treatment of Tuberculosis includes taking antibiotics such as isoniazid, rifampicin, pyrazinamide and ethambutol. Pyrazinamide and ethambutol were taken everyday for two months while isoniazid and rifampicin were taken everyday for six months or more. Mycobacterium is very strong bacteria so it is important not to skip a dose because bacteria will become resistant to the antibiotics and it will become difficult to treat. Antibiotic resistance means that the medicine can no longer kill the bacteria that they meant to fight.

Thanks that the result of our chest x ray is negative from tuberculosis.  According to our result lungs are clear.

Primary Complex Symptoms and Treatment

My 5 years old daughter was diagnosed from primary complex 20 days ago, she is now taking HZ2 pedia kit from Unilab. It contains Rifampicin, pyrazinamide and isoniazid.  At first the pedia dosage for the three meds are 5 ml she weighted 19 kilos, but now she loss 2 kilos that’s why she down to 4 ml. 

Rifampicin and isoniazid should be taken empty stomach.  That means it should be taken 1 hr or 2 hrs before meal or after meal while pyrazinamide can be taken anytime.  Some parents would prefer to drink the two meds before breakfast but in my case I prefer to take it between breakfast and lunchtime. At second visit, our pedia advise it to take at bedtime. It is important to take these three medicines religiously meaning don’t skip and should be taken everyday for the entire six months.  If you skip, bacteria may become resistance to these drugs and later on needs more other strong medicines.

Pyrazinamide is taken for only two months while Rifampicin and isoniazid is taken for six months.  If there is no improvement, it will have an extension of three months for the total of nine months. One indication that your child is cured from primary complex is weight gain and no other symptoms of PTB.

The symptoms of primary complex include enlarged lymph nodes in the neck area, prolonged cough that doesn’t resolve with treatment, low grade afternoon fever, weight loss, loss of appetite.  In order to diagnose primary complex is by positive PPD or tuberculin test and chest xray.  If there is positive PPD and negative xray, the child should is also require to take one type of anti-TB medicines which is the isoniazid for six months also. PPD or tuberculin test positive result means that there is an TB bacteria exposure that why it is also recommended to take medicine for prevention.

If your kid is diagnosed primary complex, it is essential to treat it immediately without delay because untreated tuberculosis may lead to complications which can be life threatening.

Causes of Recurrent Primary Complex (PTB)

I often heard my friends who told me that their daughter is suffer from recurrent Primary Complex or recurrent PTB.

As of now my daughter is under medication for Primary Complex. She already consumed one month and I am worried if PTB is keep on coming back even though it already treated.  So I ask my pediatrician about this, she told me that re-infected can occur if
The primary source is not treated and not be able to take medication properly or incomplete treatment.  Just like us, I and my husband also advised to have chest x-ray so that she will able to locate the source of infection. Our chest x-ray came out negative so we really don’t know.

The three drugs, Isoniazid, Rifampicin and  Pyrazinamide should be taken for about 6 months and more depending on the evaluation of your physician.  Pyrazinamide is taken for the initial of two months while Isoniazid and Rifampicin is continued for four months and more.  An indication that your kid or child is responding to the TB medication and is getting healed is weight gain.  Symptoms of PTB includes weight loss, on and off cough, loss of appetite, low grade afternoon or night fever, etc. 


In order to avoid the recurrence of Primary complex, make sure to give medicines everyday religiously for six months or more. If not, bacteria will develop into more med resistant kind.  Also, as much as possible, find the source of infection, make sure to your household member will be screening for PTB or Tuberculosis since the infection is came from adult.  Other causes of re-infected PTB is a weak immune system so be sure to build strong immune system of your children. 

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